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Vytrus Biotech has reported quantifying two forms of plant-derived PDRN in its hair-care actives, extending a portfolio it says spans skin, scalp and hair. The company cites clinical, ex vivo and other product studies, but the source report does not provide study sizes, full methods or independent verification of the results.
Vytrus Biotech says it has quantified two forms of plant-derived PDRN in its hair-care actives, extending its ingredient portfolio across skin, scalp and hair. The company also reported product-study findings on hair density, scalp redness and curly-hair performance, though the supplied report does not give study sizes or full protocols.
Vytrus describes its approach as using PDRN naturally present in plant stem-cell actives in two forms: Phyto-PDRN, DNA fragments the company says act at the cell surface, and ExoPDRN™, which it describes as PDRN naturally encapsulated in plant exosomes. The company presents them as complementary, with activity at the cell surface and inside cells. The source report does not provide independent evidence for that mechanism.
For hair care, Vytrus says it quantified both forms in Capilia Longa™, derived from Curcuma longa stem cells, and Elaya Renova™, derived from Mediterranean olive stem cells. The company describes Capilia Longa as clinically proven to reduce hair loss and increase hair density, but the report supplies no participant numbers, measurement details or trial design. It says scientific literature associates PDRN with hair growth; that association does not establish that this ingredient caused the reported product effects.
Vytrus also reports that ExoPDRN™ in Elaya Renova reduced scalp redness compared with placebo. Separately, it cites an ex vivo curly-hair study in which one leave-on application improved hydration, reduced combing effort and frizz under high humidity, and increased curl definition. These findings relate to specific product tests; the supplied material does not describe their methods or provide numerical results.
A Plant-Based Portfolio for Hair and Skin
The announcement matters to cosmetics formulators because it positions plant-derived PDRN as a shared ingredient platform for products aimed at skin, scalp and hair, rather than a single skin-care application. Vytrus says the portfolio covers soothing and regenerating skin care, scalp comfort, hair-loss prevention, hair density and curly-hair care. That may give manufacturers additional ingredient concepts to evaluate, but the report does not establish comparative performance against other ingredients or treatments.
For consumers, the reported outcomes are relevant but should be read as company-reported product findings, not proof that all products containing plant PDRN produce the same effects. Hair loss and scalp redness can have multiple causes, and the source offers no clinical guidance for people experiencing either concern. The announcement is therefore more directly a development in cosmetic ingredient research and marketing than a change in medical care.
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Earlier Skin Studies and New Hair Data
The hair-care claims build on skin-related plant PDRN studies that Vytrus presented in April, according to the supplied report. It names two skin actives: Centella Reversa™, which combines Phyto-PDRN and ExoPDRN™ and is marketed for skin rejuvenation, regeneration and cellular DNA protection, and Sensia Carota™, which contains Phyto-PDRN and is marketed for sensitive skin and redness.
The report describes the products and their claimed effects but does not provide the April presentation date, full study publications or independent assessments. Its references to clinical and ex vivo results should be distinguished: a clinical study involving people and an ex vivo test outside a living body are different kinds of evidence and cannot be treated as interchangeable.
““For the first time, Vytrus has quantified Phyto-PDRN and ExoPDRN™ in its hair care actives.””
— Vytrus Biotech, as described in the Cosmetics Business report
Study Methods and Results Still Missing
The supplied report does not state how many people or samples were included in the studies, how outcomes were measured, how long any effects lasted, or whether the findings have been published in peer-reviewed research. It also provides no numerical effect sizes for hair density, hair loss, scalp redness, hydration, combing effort, frizz or curl definition.
It is also unclear what “for the first time” refers to beyond Vytrus’ own quantification of these forms in its hair-care actives. The source does not identify the analytical method or provide data that would allow readers to assess the amount of PDRN present. The reported association between PDRN and hair growth in scientific literature is not, by itself, evidence that these products prevent hair loss or increase density.
Further Data Needed to Assess Claims
Vytrus says formulators can contact the company for further information. The next useful evidence would include study protocols, sample sizes, measured results and publication details, alongside clear information about how the ingredient quantities were determined. No additional study, regulatory decision or product launch date is specified in the supplied report.
Until those details are available, the findings should be treated as company-reported results for particular ingredients and test conditions. Readers concerned about persistent hair loss or scalp symptoms should seek advice from a qualified health professional rather than rely on cosmetic product claims alone.
Key Questions
What has Vytrus announced?
Vytrus says it has quantified Phyto-PDRN and ExoPDRN™ in its hair-care actives and reports studies involving hair density, scalp redness and curly-hair performance.
What are Phyto-PDRN and ExoPDRN?
In Vytrus’ description, Phyto-PDRN consists of DNA fragments that act at the cell surface, while ExoPDRN™ is PDRN naturally encapsulated in plant exosomes. The supplied report does not independently verify this proposed mechanism.
Do the findings prove plant PDRN prevents hair loss?
No. Vytrus describes Capilia Longa™ as clinically proven to reduce hair loss and increase hair density, but the source report does not include the study design, participant numbers or numerical outcomes needed to assess that claim. It does not establish that all plant PDRN products prevent hair loss.
What evidence is available for curly hair?
Vytrus reports an ex vivo study in which one leave-on application of Elaya Renova™ improved hydration and curl definition and reduced combing effort and frizz, including under high humidity. The report does not provide the test protocol or numerical results.
Source: cosmeticsbusiness.com
